Article Sidebar
Main Article Content
Abstract
ABSTRACT
Introduction. Incidence of head injuries is also quite high in Indonesia, around 1.4 million cases per year with a mortality rate of 15-20% in the population aged 5 to 35 years. Head injuries are commonly divided into two separate time periods namely primary and secondary brain injuries. Primary brain injury is physical damage to the parenchyma (tissue and blood vessels) that occurs during a traumatic event, thus causing compression of the surrounding brain tissue. Secondary brain injury is a continuation of the results of primary brain injury with the main complications of brain injury in the following hours and days. This study was aimed to asses the benefits of administration of mannitol in cases of severe head injury in South Sumatra, Indonesia.
Methods. This research was a clinical trial without comparison by looking at hematocrit levels in patients with severe head injuries with intracranial hypertension before and after given mannitol therapy. Data analysis was performed with IBM SPSS Version 23. Data was presented in the form of narrative tables. Then the paired T test was performed. P value <0.05.
Results. From 39 research subjects, the age of the subjects ranged between 6-88 years with an average of 33 years. Based on sex there were 28 male sufferers (71.8%) and there were 11 female sufferers 28.2%. GCS varies from 3 to GCS 8 intra-cranial abnormalities. From 39 research subjects with severe head injury without surgery, a hematocrit examination was performed before, after 10 minutes and 6 hours of injection of mannitol bolus 1 g / kg body weight. It was obtained that averaged hematocrit before mannitol administration was 34, after 10 minutes was 33 and after 6 hours was 35.
Conclusion. There is a decrease in hematocrit levels after administration of bolus mannitol 1 g / kg BW at the beginning of mannitol administration and hematocrit will increase again after 6 hours of mannitol administration
Keywords
Article Details
1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2.Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3.Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.