Compatibility between MRI Examination and Histopathological Findings in Tuberculous Spondylitis Patients at Dr. Mohammad Hoesin Palembang

Abstract

Tuberculous spondylitis or Pott's disease is an infection disease caused by Mycobacterium tuberculosis that affects the spine. Tuberculous spondylitis is the most dangerous form of musculoskeletal tuberculosis because it can cause serious morbidity due to bone destruction, deformity and paraplegia, therefore early diagnosis is very important. This study aims to determine the compability between clinical diagnosis and histopathological findings in patients with tuberculous spondylitis. This research is a diagnostic research conducted in polyclinic, orthopedic surgery, radiology room and Pathology laboratory of Mohammad Hoesin Hospital Palembang. The sample in this study were all patients with suspected being diagnosed tuberculous spondylitis, who underwent an MRI examination and surgery and histopathological examination. There were 15 patients suspected of being diagnosed with tuberculous spondylitis. In this study, histopathologically, there were 12 samples with a diagnosis of tuberculous spondylitis, while based on MRI, 14 samples were obtained with a diagnosis of tuberculous spondylitis. The results of the MRI examination had a sensitivity of 100%, specificity 33.3%, PPV 85.7%, NPV 100%, positive Likelihood ratio 1.499 and negative Likelihood ratio 0. The accuracy between MRI examination and histopathological findings in tuberculous spondylitis patients was 0.867 with this test. Kappa obtained a conformity value of 0.444 with a significance of 0.038 (p < 0.05). The accuracy between MRI examination and histopathological findings in patients with tuberculous spondylitis had a very good of reliability with a moderate degree of compability.